150 years of booms, busts, and a whole lot of newborns.

The heart of San Francisco beats to its own rhythm, and it always has.

Through baby booms, housing booms, and even tech booms, we’ve seen it all.


And yet, this city can still surprise us. Its resilience. Its love. Its pride.


We were here, through natural disasters, pandemics, and plagues. For the birth of new ideas, new communities, and of course, newborns. And today, we are still here, providing compassionate care for the whole person, and the whole city.


And now, Zuckerberg San Francisco General is planning for the next 150 years. 


150 years keeping the heart of San Francisco beating strong.

150 years of care

ZSFG150 timeline group of nurses

Learn more about the rich history of Zuckerberg San Francisco Hospital and Trauma Center. For 150 years, countless stories of compassion are matched only by impressive innovations in medicine and beyond.


Explore these notable events in our public hospital’s 150-year history.



Explore Our History

A Legacy of Care

On August 28, 1872, the City of San Francisco opened the doors to the City and County Hospital at 23rd and Potrero Streets, making an investment in public health that would withstand plagues and earthquakes, population booms and great inventions. 150 years later, Zuckerberg San Francisco General Hospital still stands, keeping the heart of this city beating strong. 


We are proud to celebrate ZSFG’s 150th anniversary of providing essential health care to all San Franciscans. As the only Level 1 trauma center in the City and County, ZSFG is always prepared to care for this city in times of crisis, but also as we work towards a healthier future.


Learn more about this 150-year legacy.

Help prepare us for the next 150 years.

Donate Today

Join us as we celebrate our past and plan for a more equitable future.


150 years keeping the heart of San Francisco beating strong.

Bank of America Celebrates 150 Years of Care at ZSFG.

The Foundation is thrilled to announce this years presenting sponsor, Bank of America. Thank you for your generous contribution and your continued dedication to improving health care and health equity at Zuckerberg San Francisco General.

ZSFG150 Thank you to our sponsors