ZSFG exterior from Potrero Street

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Addiction Care Team in B25 Causeway ZSFG

A Legacy of Exceptional Public Health

ZSFG MRI machine nurse and patient

Zuckerberg San Francisco General Hospital and Trauma Center (ZSFG) has been the leader in San Francisco’s comprehensive commitment to exceptional public health for more than 150 years. With a mission to provide exceptional health care and trauma services for the 1.5 million residents of San Francisco and northern San Mateo County, regardless of their immigration or socioeconomic status, it has been both an everyday resource for those in need and a safeguard for the entire populace in times of crisis.


In the most pivotal moments of our city’s history—from providing shelter and treatment following the San Francisco Earthquake of 1906, to opening the first inpatient and outpatient AIDS units in the country in 1981, to treating one-third of the city’s COVID-19 cases today—the exceptional health care providers at ZSFG have served and protected the community all while developing worldwide standards of care. 


For more than 150 years, ZSFG has worked in concert with the city’s Department of Public Health and U.C. San Francisco to provide top-notch physicians and the best possible patient experience at ZSFG. All ZSFG doctors are UCSF faculty and ZSFG is one of three training sites for UCSF medical interns and residents. ZSFG also trains nurses, pharmacists, and dentists from UCSF and other schools.


This partnership provides a unique opportunity for a research institution to work directly with patients in the community. The physicians that work at ZSFG are part of the university, but their hearts belong to the patient population they serve through their work at the hospital. 

Commitment to Equity and Innovation

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Our legacy of health equity is built on a foundation of mutual trust between the hospital and the community. We believe in core values like diversity, compassion, and a commitment to providing the best care to the most vulnerable in our community, including the uninsured, the undocumented, the elderly, expectant mothers, accident victims, and those in need of mental health care. 


In addition to research, we know it takes hands-on action to tackle San Francisco’s toughest public health challenges, so we deliver innovative whole-person care initiatives that directly address the city’s most urgent needs while pioneering new approaches to address disparities in the quality of health care and health outcomes.


Innovation contributes to meaningful progress on critical health disparities which is why we are focused on shortening the time between research and impact —and the distance between researchers, health care providers, and patients and the communities they live in.

Impact Numbers
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Donor support brings our mission to life


Despite its close affiliation with the City of San Francisco, ZSFG is reliant on donor contributions to provide quality health care and trauma services and ensure we have the resources and infrastructure to address the unexpected disasters and diseases of the future.


Donor support enables all that we do, including advancing community wellness through lifesaving and life-affirming care, pioneering new methods and models of treatment, and educating the next generation of dedicated health care providers. 


We are driven to help the communities who bear the burden of systemic inequalities and are most impacted by illness and disease, and we are resolute that prevention and care reach all members of our community. We invite you to be a partner in our mission to support and fund excellence in patient care and innovation at Zuckerberg San Francisco General Hospital and Trauma Center. 

We believe in equity, access, and quality health care for all. Will you join us?